Lipid-lowering agents. Evidence of morbidity and mortality.

The essay should be very scientific using guidelines and proper references.

The client’s suggestion is to focus on:
Prevalence
Pathogenesis of atherosclerosis
Treatments of hypercholesterolemia ( mechanism of action, uses, side effects, role in lipid profile, the link with morbidity and mortality)
1-Statin therapy
2-Non-statin therapies: Fibric acid derivatives, Bile acid sequestrants, Cholesterol absorption inhibitors, Nicotinic acid, Dietary supplement as fish oil.

The main focus of the essay should be on the evidence and role of lipid-lowering agents in the morbidity and mortality using guidelines. 

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