Renaissance Venice: How did Venice at the height of their maritime empire in 1516 lose power over the course the eventual 350 years till the unification of Italy?

The prompt question is how did Venice at the height of their maritime empire in 1516 lose power over the course the eventual 350 years till the unification of Italy? I’d like to have 6 or 7 sources all cited in Chicago style. Also include 1 or 2 works of art from Venice during this time period and try to explain why it showcases the society of Venice at the diminishing empire