biology; biochemical and mechanical parameters of chondrocyte
biology; biochemical and mechanical parameters of chondrocyte
How the biochemical and mechanical parameters of chondrocyte/agarose constructs are influenced by the gel concentration and culture period.
Please discuss:
Discussion should include further studies on how to improve nutrient utilisation, prevent oxygen/glucose gradients (bioreactors?) and maximise anabolic (GAGs) signalling events in chondrocyte/agarose constructs. You should give a broad discussion involving the important concepts in mechanobiology (1000 words)